Ipratropium bromide is useful in bronchial asthma because of
1) Anticholinergic effect
2) Vasodilator properties
3) Antiallergic action
4) Stabilization of mast cells
📝 Explanation:
Ipratropium (as ipratropium bromide, trade name Atrovent) is an anticholinergic drug administered by inhalation for the treatment of obstructive lung diseases.
It acts by blocking muscarinic receptors in the lung, inhibiting bronchoconstriction and mucus secretion.
It is a non-selective muscarinic antagonist, and does not diffuse into the blood, which prevents systemic side effects.
Ipratropium is a derivative of atropine[1] but is a quaternary amine and therefore does not cross the blood-brain barrier