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NEET MDS Quiz - Practice Test

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pharmacology - 3 Questions

1
Pharmacology
Albendazole is effective against infection with all of the following except- 1. Ascariasis 2. Neurocysticercosis 3. Echinococcus granulosus 4. Schistosomiasis

📝 Explanation:

Albendazole is not effective against Schistosomiasis, which is caused by a parasitic worm.

2
Pharmacology

A medication that is associated with gingivitis 

1)  phenytoin
2)  carbamazepine 
3)  propranolol
4)  diazepam

📝 Explanation:

Gingivitis is a form of periodontal disease. Periodontal disease is when inflammation and infection destroy the tissues that support the teeth, including the gingiva (gums), the periodontal ligaments, and the tooth sockets (alveolar bone Malocclusion of teeth (misaligned teeth), rough edges of fillings, and ill fitting or unclean mouth appliances (such as orthodontic appliances, dentures, bridges, and crowns) can irritate the gums and increase the risk of gingivitis.

Medications such as phenytoin and birth control pills, and ingestion of heavy metals such as lead and bismuth are also associated with gingivitis.

3
Pharmacology

What is a major adverse effect associated with the use of amphotericin B?
1). Hepatotoxicity
2). Bone marrow suppression
3). Gastrointestinal disturbances
4). Nephrotoxicity

📝 Explanation:

Amphotericin B binds to ergosterol in the fungal cell membrane, causing pore formation and fungal cell death. However, it is well known for causing dose-dependent nephrotoxicity due to damage to renal tubular cells. Patients receiving amphotericin B require regular monitoring of serum creatinine, electrolytes (especially potassium and magnesium), and renal function throughout therapy.

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