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NEET MDS Quiz - Practice Test

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pathology - 3 Questions

1
Pathology

Which of the following blood components can be expected to increase with disseminated intravascular coagulation?

1) Factor V
2) Fibrin degradation products
3) Fibrinogen
4) Plasminogen

📝 Explanation:

Fibrin degradation products increase in disseminated intravascular coagulation (DIC) due to the breakdown of fibrin clots.

2
Pathology

Clinical hallmark of hemophilia is:
1) Hemarthrosis with easy bruising and massive hemorrhage after trauma, petechiae absent
2) Petechiae and mucosal bleeding
3) Thrombocytopenia
4) Deep vein thrombosis

📝 Explanation:

Robbins: Tendency to easy bruising and massive hemorrhage after trauma/operative procedures. Spontaneous hemorrhages in tissues subject to mechanical stress - particularly joints - recurrent hemarthrosis ? progressive deformities, crippling. Petechiae characteristically absent (petechiae seen in platelet disorders). Prolonged bleeding time in platelet defect, prolonged aPTT in hemophilia.

3
Pathology
Which of the following proteins is most likely under-expressed in this boy?
1) Late complement components
2) Transcobalamin II
3) Integrins
4) ?2-globulins

📝 Explanation:

Integrins are likely under-expressed in this boy, as they play a crucial role in cell adhesion and signaling, and their deficiency can lead to various immunological issues.

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