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pathology - 3 Questions
Which of the following blood components can be expected to increase with disseminated intravascular coagulation?
1) Factor V2) Fibrin degradation products3) Fibrinogen4) Plasminogen
Fibrin degradation products increase in disseminated intravascular coagulation (DIC) due to the breakdown of fibrin clots.
Clinical hallmark of hemophilia is: 1) Hemarthrosis with easy bruising and massive hemorrhage after trauma, petechiae absent 2) Petechiae and mucosal bleeding 3) Thrombocytopenia 4) Deep vein thrombosis
Robbins: Tendency to easy bruising and massive hemorrhage after trauma/operative procedures. Spontaneous hemorrhages in tissues subject to mechanical stress - particularly joints - recurrent hemarthrosis ? progressive deformities, crippling. Petechiae characteristically absent (petechiae seen in platelet disorders). Prolonged bleeding time in platelet defect, prolonged aPTT in hemophilia.
Integrins are likely under-expressed in this boy, as they play a crucial role in cell adhesion and signaling, and their deficiency can lead to various immunological issues.